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T-cell co-stimulatory pathways in autoimmunity

T-cell activation and differentiation depend on the signal strength received by the T-cell receptor and on signals provided by co-stimulatory molecules. The most prominent co-stimulatory molecule is CD28, which controls the activation of naïve and memory T cells by antigen presented on professional...

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Detalles Bibliográficos
Autores principales: Goronzy, Jörg J, Weyand, Cornelia M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582810/
https://www.ncbi.nlm.nih.gov/pubmed/19007423
http://dx.doi.org/10.1186/ar2414