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T-cell co-stimulatory pathways in autoimmunity
T-cell activation and differentiation depend on the signal strength received by the T-cell receptor and on signals provided by co-stimulatory molecules. The most prominent co-stimulatory molecule is CD28, which controls the activation of naïve and memory T cells by antigen presented on professional...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582810/ https://www.ncbi.nlm.nih.gov/pubmed/19007423 http://dx.doi.org/10.1186/ar2414 |