Induction of cell retraction by the combined actions of Abl–CrkII and Rho–ROCK1 signaling

Dynamic modulation of cell adhesion is integral to a wide range of biological processes. The small guanosine triphosphatase (GTPase) Rap1 is an important regulator of cell–cell and cell–matrix adhesions. We show here that induced expression of activated Abl tyrosine kinase reduces Rap1-GTP levels th...

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Detalles Bibliográficos
Autores principales: Huang, XiaoDong, Wu, Diana, Jin, Hua, Stupack, Dwayne, Wang, Jean Y.J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582888/
https://www.ncbi.nlm.nih.gov/pubmed/19001122
http://dx.doi.org/10.1083/jcb.200801192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582888/
https://www.ncbi.nlm.nih.gov/pubmed/19001122
http://dx.doi.org/10.1083/jcb.200801192

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