Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

Cardiolipin is a mitochondria-specific phospholipid known to be intimately involved with apoptosis. However, the lack of appropriate cellular models to date restricted analysis of its role in cell death. The maturation of cardiolipin requires the transacylase tafazzin, which is mutated in the human...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonzalvez, Francois, Schug, Zachary T., Houtkooper, Riekelt H., MacKenzie, Elaine D., Brooks, David G., Wanders, Ronald J.A., Petit, Patrice X., Vaz, Frédéric M., Gottlieb, Eyal
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582890/
https://www.ncbi.nlm.nih.gov/pubmed/19001123
http://dx.doi.org/10.1083/jcb.200803129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582890/
https://www.ncbi.nlm.nih.gov/pubmed/19001123
http://dx.doi.org/10.1083/jcb.200803129

Ejemplares similares