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Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
The establishment of apical–basal polarity within a single cell and throughout a growing tissue is a key feature of epithelial morphogenesis. To examine the underlying mechanisms, the human intestinal epithelial cell line Caco-2 was grown in a three-dimensional matrix to generate a cystlike structur...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582895/ https://www.ncbi.nlm.nih.gov/pubmed/19001128 http://dx.doi.org/10.1083/jcb.200807121 |