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Uncorrected Nucleotide Bias in mtDNA Can Mimic the Effects of Positive Darwinian Selection
The relative rates of nucleotide substitution at synonymous and nonsynonymous sites within protein-coding regions have been widely used to infer the action of natural selection from comparative sequence data. It is known, however, that mutational and repair biases can affect rates of evolution at bo...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582980/ https://www.ncbi.nlm.nih.gov/pubmed/18842686 http://dx.doi.org/10.1093/molbev/msn224 |