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Uncorrected Nucleotide Bias in mtDNA Can Mimic the Effects of Positive Darwinian Selection

The relative rates of nucleotide substitution at synonymous and nonsynonymous sites within protein-coding regions have been widely used to infer the action of natural selection from comparative sequence data. It is known, however, that mutational and repair biases can affect rates of evolution at bo...

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Detalles Bibliográficos
Autores principales: Albu, Mihai, Min, Xiang Jia, Hickey, Donal, Golding, Brian
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582980/
https://www.ncbi.nlm.nih.gov/pubmed/18842686
http://dx.doi.org/10.1093/molbev/msn224