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Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation

The state of the transcriptome reflects a balance between mRNA production and degradation. Yet how these two regulatory arms interact in shaping the kinetics of the transcriptome in response to environmental changes is not known. We subjected yeast to two stresses, one that induces a fast and transi...

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Detalles Bibliográficos
Autores principales: Shalem, Ophir, Dahan, Orna, Levo, Michal, Martinez, Maria Rodriguez, Furman, Itay, Segal, Eran, Pilpel, Yitzhak
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583085/
https://www.ncbi.nlm.nih.gov/pubmed/18854817
http://dx.doi.org/10.1038/msb.2008.59