Evaluation of Clustering and Genotype Distribution for Replication in Genome Wide Association Studies: The Age-Related Eye Disease Study

Genome-wide association studies (GWASs) assess correlation between traits and DNA sequence variation using large numbers of genetic variants such as single nucleotide polymorphisms (SNPs) distributed across the genome. A GWAS produces many trait-SNP associations with low p-values, but few are replic...

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Detalles Bibliográficos
Autores principales: Edwards, Albert O., Fridley, Brooke L., James, Katherine M., Sharma, Anil S., Cunningham, Julie M., Tosakulwong, Nirubol
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583911/
https://www.ncbi.nlm.nih.gov/pubmed/19043567
http://dx.doi.org/10.1371/journal.pone.0003813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583911/
https://www.ncbi.nlm.nih.gov/pubmed/19043567
http://dx.doi.org/10.1371/journal.pone.0003813

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