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Evaluation of Clustering and Genotype Distribution for Replication in Genome Wide Association Studies: The Age-Related Eye Disease Study
Genome-wide association studies (GWASs) assess correlation between traits and DNA sequence variation using large numbers of genetic variants such as single nucleotide polymorphisms (SNPs) distributed across the genome. A GWAS produces many trait-SNP associations with low p-values, but few are replic...
Autores principales: | Edwards, Albert O., Fridley, Brooke L., James, Katherine M., Sharma, Anil S., Cunningham, Julie M., Tosakulwong, Nirubol |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583911/ https://www.ncbi.nlm.nih.gov/pubmed/19043567 http://dx.doi.org/10.1371/journal.pone.0003813 |
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