Formation and Growth of Oligomers: A Monte Carlo Study of an Amyloid Tau Fragment

Small oligomers formed early in the process of amyloid fibril formation may be the major toxic species in Alzheimer's disease. We investigate the early stages of amyloid aggregation for the tau fragment AcPHF6 (Ac-VQIVYK-NH2) using an implicit solvent all-atom model and extensive Monte Carlo si...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Da-Wei, Mohanty, Sandipan, Irbäck, Anders, Huo, Shuanghong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583953/
https://www.ncbi.nlm.nih.gov/pubmed/19057640
http://dx.doi.org/10.1371/journal.pcbi.1000238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583953/
https://www.ncbi.nlm.nih.gov/pubmed/19057640
http://dx.doi.org/10.1371/journal.pcbi.1000238

Ejemplares similares