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Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts

We investigated the role of polyol pathway enzymes aldose reductase (AR) and sorbitol dehydrogenase (SDH) in mediating injury due to ischemia-reperfusion (IR) in Type 2 diabetic BBZ rat hearts. Specifically, we investigated, (a) changes in glucose flux via cardiac AR and SDH as a function of diabete...

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Detalles Bibliográficos
Autores principales: Li, Qing, Hwang, Yuying C, Ananthakrishnan, Radha, Oates, Peter J, Guberski, Dennis, Ramasamy, Ravichandran
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584021/
https://www.ncbi.nlm.nih.gov/pubmed/18957123
http://dx.doi.org/10.1186/1475-2840-7-33