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Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts

We investigated the role of polyol pathway enzymes aldose reductase (AR) and sorbitol dehydrogenase (SDH) in mediating injury due to ischemia-reperfusion (IR) in Type 2 diabetic BBZ rat hearts. Specifically, we investigated, (a) changes in glucose flux via cardiac AR and SDH as a function of diabete...

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Detalles Bibliográficos
Autores principales:	Li, Qing, Hwang, Yuying C, Ananthakrishnan, Radha, Oates, Peter J, Guberski, Dennis, Ramasamy, Ravichandran
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584021/ https://www.ncbi.nlm.nih.gov/pubmed/18957123 http://dx.doi.org/10.1186/1475-2840-7-33

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