Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease

BACKGROUND: Transcriptional dysregulation is an early, key pathogenic mechanism in Huntington's disease (HD). Therefore, gene expression analyses have biomarker potential for measuring therapeutic efficacy in pre-clinical trials, particularly those aimed at correcting gene expression abnormalit...

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Detalles Bibliográficos
Autores principales: Benn, Caroline L, Fox, Helen, Bates, Gillian P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584034/
https://www.ncbi.nlm.nih.gov/pubmed/18954449
http://dx.doi.org/10.1186/1750-1326-3-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584034/
https://www.ncbi.nlm.nih.gov/pubmed/18954449
http://dx.doi.org/10.1186/1750-1326-3-17

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