First Evidence of Genetic Association Between AKT2 and Polycystic Ovary Syndrome

OBJECTIVE—Insulin resistance has been reported in up to 70% of women with polycystic ovary syndrome (PCOS). Physiologic and genetic data currently implicate post–insulin receptor signaling defects in substrates such as glycogen synthase kinase 3β (GSK3β). The AKT2 gene was chosen as a candidate for...

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Detalles Bibliográficos
Autores principales: Goodarzi, Mark O., Jones, Michelle R., Chen, Yii-Der I., Azziz, Ricardo
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Epidemiology/Health Services Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584182/
https://www.ncbi.nlm.nih.gov/pubmed/18768676
http://dx.doi.org/10.2337/dc08-0532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584182/
https://www.ncbi.nlm.nih.gov/pubmed/18768676
http://dx.doi.org/10.2337/dc08-0532

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