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Immunological Mechanisms Mediating Hantavirus Persistence in Rodent Reservoirs

Hantaviruses, similar to several emerging zoonotic viruses, persistently infect their natural reservoir hosts, without causing overt signs of disease. Spillover to incidental human hosts results in morbidity and mortality mediated by excessive proinflammatory and cellular immune responses. The mecha...

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Detalles Bibliográficos
Autores principales: Easterbrook, Judith D., Klein, Sabra L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584234/
https://www.ncbi.nlm.nih.gov/pubmed/19043585
http://dx.doi.org/10.1371/journal.ppat.1000172