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Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis

BACKGROUND: Accurate staging of rectal tumors is essential for making the correct treatment choice. In a previous study, we found that loss of 17p, 18q and gain of 8q, 13q and 20q could distinguish adenoma from carcinoma tissue and that gain of 1q was related to lymph node metastasis. In order to fi...

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Detalles Bibliográficos
Autores principales: Lips, Esther H, van Eijk, Ronald, de Graaf, Eelco JR, Oosting, Jan, de Miranda, Noel FCC, Karsten, Tom, van de Velde, Cornelis J, Eilers, Paul HC, Tollenaar, Rob AEM, van Wezel, Tom, Morreau, Hans
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584339/
https://www.ncbi.nlm.nih.gov/pubmed/18959792
http://dx.doi.org/10.1186/1471-2407-8-314