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Tubulin Dimers Oligomerize before Their Incorporation into Microtubules

In the presence of GTP, purified dimers of α- and β-tubulin will interact longitudinally and laterally to self-assemble into microtubules (MTs). This property provides a powerful in vitro experimental system to describe MT dynamic behavior at the micrometer scale and to study effects and functioning...

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Detalles Bibliográficos
Autores principales: Mozziconacci, Julien, Sandblad, Linda, Wachsmuth, Malte, Brunner, Damian, Karsenti, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584370/
https://www.ncbi.nlm.nih.gov/pubmed/19043587
http://dx.doi.org/10.1371/journal.pone.0003821