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Tubulin Dimers Oligomerize before Their Incorporation into Microtubules
In the presence of GTP, purified dimers of α- and β-tubulin will interact longitudinally and laterally to self-assemble into microtubules (MTs). This property provides a powerful in vitro experimental system to describe MT dynamic behavior at the micrometer scale and to study effects and functioning...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584370/ https://www.ncbi.nlm.nih.gov/pubmed/19043587 http://dx.doi.org/10.1371/journal.pone.0003821 |