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Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells

BACKGROUND: Alterations in the processing of the genetic information in carcinogenesis result from stable genetic mutations or epigenetic modifications. It is becoming clear that nucleosomal histones are central to proper gene expression and that aberrant DNA methylation of genes and histone methyla...

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Detalles Bibliográficos
Autores principales: Watanabe, Hideo, Soejima, Kenzo, Yasuda, Hiroyuki, Kawada, Ichiro, Nakachi, Ichiro, Yoda, Satoshi, Naoki, Katsuhiko, Ishizaka, Akitoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584620/
https://www.ncbi.nlm.nih.gov/pubmed/18980680
http://dx.doi.org/10.1186/1475-2867-8-15