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Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells
BACKGROUND: Alterations in the processing of the genetic information in carcinogenesis result from stable genetic mutations or epigenetic modifications. It is becoming clear that nucleosomal histones are central to proper gene expression and that aberrant DNA methylation of genes and histone methyla...
Autores principales: | Watanabe, Hideo, Soejima, Kenzo, Yasuda, Hiroyuki, Kawada, Ichiro, Nakachi, Ichiro, Yoda, Satoshi, Naoki, Katsuhiko, Ishizaka, Akitoshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584620/ https://www.ncbi.nlm.nih.gov/pubmed/18980680 http://dx.doi.org/10.1186/1475-2867-8-15 |
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