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Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression

BACKGROUND: Hypoxia-inducible factor 1 alpha (HIF-1α) is involved in processes promoting carcinogenesis of many tumors. However, its role in the development of colorectal cancer is unknown. To investigate the significance of HIF-1α during colorectal carcinogenesis and progression we examined its exp...

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Detalles Bibliográficos
Autores principales: Simiantonaki, Nektaria, Taxeidis, Marios, Jayasinghe, Caren, Kurzik-Dumke, Ursula, Kirkpatrick, Charles James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584660/
https://www.ncbi.nlm.nih.gov/pubmed/18983642
http://dx.doi.org/10.1186/1471-2407-8-320