APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

APOBEC3G (A3G) is a host cytidine deaminase that, in the absence of Vif, restricts HIV-1 replication and reduces the amount of viral DNA that accumulates in cells. Initial studies determined that A3G induces extensive mutation of nascent HIV-1 cDNA during reverse transcription. It has been proposed...

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Detalles Bibliográficos
Autores principales: Bishop, Kate N., Verma, Mohit, Kim, Eun-Young, Wolinsky, Steven M., Malim, Michael H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584787/
https://www.ncbi.nlm.nih.gov/pubmed/19057663
http://dx.doi.org/10.1371/journal.ppat.1000231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584787/
https://www.ncbi.nlm.nih.gov/pubmed/19057663
http://dx.doi.org/10.1371/journal.ppat.1000231

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