Cargando…

APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

APOBEC3G (A3G) is a host cytidine deaminase that, in the absence of Vif, restricts HIV-1 replication and reduces the amount of viral DNA that accumulates in cells. Initial studies determined that A3G induces extensive mutation of nascent HIV-1 cDNA during reverse transcription. It has been proposed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bishop, Kate N., Verma, Mohit, Kim, Eun-Young, Wolinsky, Steven M., Malim, Michael H.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584787/ https://www.ncbi.nlm.nih.gov/pubmed/19057663 http://dx.doi.org/10.1371/journal.ppat.1000231

Ejemplares similares

Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G
por: Iwatani, Yasumasa, et al.
Publicado: (2007)

Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted anti-viral functions of APOBEC3G
por: Pollpeter, Darja, et al.
Publicado: (2017)

Mov10, an APOBEC3G-interacting RNA-binding protein, inhibits HIV-1 infection
por: Arjan, Shetal, et al.
Publicado: (2011)

RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1
por: Huthoff, Hendrik, et al.
Publicado: (2009)

The Roles of APOBEC3G Complexes in the Incorporation of APOBEC3G into HIV-1
por: Ma, Jing, et al.
Publicado: (2013)

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G
por: Stanley, David J., et al.
Publicado: (2012)

APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication
por: Li, Lin, et al.
Publicado: (2008)

Human APOBEC3 Induced Mutation of Human Immunodeficiency Virus Type-1 Contributes to Adaptation and Evolution in Natural Infection
por: Kim, Eun-Young, et al.
Publicado: (2014)

Degradation-Independent Inhibition of APOBEC3G by the HIV-1 Vif Protein
por: Stupfler, Benjamin, et al.
Publicado: (2021)

APOBEC3G and APOBEC3F rarely co-mutate the same HIV genome
por: Ebrahimi, Diako, et al.
Publicado: (2012)

APOBEC3G and APOBEC3F Require an Endogenous Cofactor to Block HIV-1 Replication
por: Han, Yanxing, et al.
Publicado: (2008)

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1
por: Apolonia, Luis, et al.
Publicado: (2015)

Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase
por: Adolph, Madison B., et al.
Publicado: (2013)

Rationalisation of the Differences between APOBEC3G Structures from Crystallography and NMR Studies by Molecular Dynamics Simulations
por: Autore, Flavia, et al.
Publicado: (2010)

Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance
por: Mohammadzadeh, Nazanin, et al.
Publicado: (2019)

The cellular source for APOBEC3G's incorporation into HIV-1
por: Ma, Jing, et al.
Publicado: (2011)

Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization
por: Khan, Mohammad A, et al.
Publicado: (2009)

Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C
por: Soliman, Shimaa H. A., et al.
Publicado: (2023)

HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation
por: Mercenne, Gaëlle, et al.
Publicado: (2010)

Strand Transfer and Elongation of HIV-1 Reverse Transcription Is Facilitated by Cell Factors In Vitro
por: Warrilow, David, et al.
Publicado: (2010)

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA
por: Friew, Yeshitila N, et al.
Publicado: (2009)

HIV-1 Vif inhibits G to A hypermutations catalyzed by virus-encapsidated APOBEC3G to maintain HIV-1 infectivity
por: Wang, Yudi, et al.
Publicado: (2014)

APOBEC3G & HTLV-1: Inhibition without deamination
por: Strebel, Klaus
Publicado: (2005)

Homodimerization of APOBEC3G is required for inhibition of Alu retrotransposition
por: Iwabu, Yukie, et al.
Publicado: (2011)

Radiosensitization to γ-Ray by Functional Inhibition of APOBEC3G
por: Tong, Ying, et al.
Publicado: (2022)

Prognostic value, immune signature and molecular mechanisms of the APOBEC family members APOBEC1, APOBEC3A, APOBEC3G and APOBEC3H in pancreatic adenocarcinoma
por: Duan, Yunjie, et al.
Publicado: (2022)

APOBEC3G encapsidation into HIV-1 virions: which RNA is it?
por: Strebel, Klaus, et al.
Publicado: (2008)

Retraction: the cellular source for APOBEC3G's incorporation into HIV-1
por: Ma, Jing, et al.
Publicado: (2011)

APOBEC3G expression and HIV-1 infection in Burkina Faso
por: Compaore, Tegwinde Rebeca, et al.
Publicado: (2018)

Newly Synthesized APOBEC3G Is Incorporated into HIV Virions, Inhibited by HIV RNA, and Subsequently Activated by RNase H
por: Soros, Vanessa B, et al.
Publicado: (2007)

Small molecules that inhibit Vif-induced degradation of APOBEC3G
por: Matsui, Masashi, et al.
Publicado: (2014)

USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
por: Pan, Ting, et al.
Publicado: (2019)

HIV-1 Vif and APOBEC3G: Multiple roads to one goal
por: Goncalves, Joao, et al.
Publicado: (2004)

The structural basis for HIV-1 Vif antagonism of human APOBEC3G
por: Li, Yen-Li, et al.
Publicado: (2023)

Aromatic disulfides as potential inhibitors against interaction between deaminase APOBEC3G and HIV infectivity factor: Inhibitors of interaction between APOBEC3G and Vif
por: Yan, Xiaoxuan, et al.
Publicado: (2022)

HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription
por: Cosnefroy, Ophélie, et al.
Publicado: (2016)

Structural insights into NusG regulating transcription elongation
por: Liu, Bin, et al.
Publicado: (2017)

Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo
por: Stavrou, Spyridon, et al.
Publicado: (2014)

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells
por: Pollpeter, Darja, et al.
Publicado: (2019)

Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?
por: Cadima-Couto, Iris, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ss5v6r3es3ae7eh6l6i5kj9kaa