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MNAR functionally interacts with both NH(2)- and COOH-terminal GR domains to modulate transactivation

Glucocorticoids are potent anti-inflammatory agents, acting through the glucocorticoid receptor (GR) to regulate target gene transcription. However, GR may also exert acute effects, including activation of signaling kinases such as c-Src and protein kinase B, possibly via the scaffold protein, modul...

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Detalles Bibliográficos
Autores principales: Kayahara, Midori, Ohanian, Jacqueline, Ohanian, Vasken, Berry, Andrew, Vadlamudi, Ratna, Ray, David W.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584814/
https://www.ncbi.nlm.nih.gov/pubmed/18682536
http://dx.doi.org/10.1152/ajpendo.90429.2008