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AICAR decreases the activity of two distinct amiloride-sensitive Na(+)-permeable channels in H441 human lung epithelial cell monolayers

Transepithelial transport of Na(+) across the lung epithelium via amiloride-sensitive Na(+) channels (ENaC) regulates fluid volume in the lung lumen. Activators of AMP-activated protein kinase (AMPK), the adenosine monophosphate mimetic AICAR, and the biguanide metformin decreased amiloride-sensitiv...

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Detalles Bibliográficos
Autores principales:	Albert, A. P., Woollhead, A. M., Mace, O. J., Baines, D. L.
Formato:	Texto
Lenguaje:	English
Publicado:	American Physiological Society 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584878/ https://www.ncbi.nlm.nih.gov/pubmed/18723760 http://dx.doi.org/10.1152/ajplung.90353.2008

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