FimH Adhesin of Type 1 Fimbriae Is a Potent Inducer of Innate Antimicrobial Responses Which Requires TLR4 and Type 1 Interferon Signalling

Components of bacteria have been shown to induce innate antiviral immunity via Toll-like receptors (TLRs). We have recently shown that FimH, the adhesin portion of type 1 fimbria, can induce the innate immune system via TLR4. Here we report that FimH induces potent in vitro and in vivo innate antimi...

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Detalles Bibliográficos
Autores principales: Ashkar, Ali A., Mossman, Karen L., Coombes, Brian K., Gyles, Carlton L., Mackenzie, Randy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585055/
https://www.ncbi.nlm.nih.gov/pubmed/19057665
http://dx.doi.org/10.1371/journal.ppat.1000233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585055/
https://www.ncbi.nlm.nih.gov/pubmed/19057665
http://dx.doi.org/10.1371/journal.ppat.1000233

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