Development of selective blockers for Ca(2+)-activated Cl(- )channel using Xenopus laevis oocytes with an improved drug screening strategy

BACKGROUND: Ca(2+)-activated Cl(- )channels (CaCCs) participate in many important physiological processes. However, the lack of effective and selective blockers has hindered the study of these channels, mostly due to the lack of good assay system. Here, we have developed a reliable drug screening me...

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Detalles Bibliográficos
Autores principales: Oh, Soo-Jin, Park, Jung Hwan, Han, Sungyu, Lee, Jae Kyun, Roh, Eun Joo, Lee, C Justin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585076/
https://www.ncbi.nlm.nih.gov/pubmed/18959787
http://dx.doi.org/10.1186/1756-6606-1-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585076/
https://www.ncbi.nlm.nih.gov/pubmed/18959787
http://dx.doi.org/10.1186/1756-6606-1-14

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