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GPRC6A Null Mice Exhibit Osteopenia, Feminization and Metabolic Syndrome
BACKGROUND: GPRC6A is a widely expressed orphan G-protein coupled receptor that senses extracellular amino acids, osteocalcin and divalent cations in vitro. The physiological functions of GPRC6A are unknown. METHODS/PRINCIPAL FINDINGS: In this study, we created and characterized the phenotype of GPR...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585477/ https://www.ncbi.nlm.nih.gov/pubmed/19050760 http://dx.doi.org/10.1371/journal.pone.0003858 |