p53 induces distinct epigenetic states at its direct target promoters

BACKGROUND: The tumor suppressor protein p53 is a transcription factor that is mutated in many cancers. Regulation of gene expression by binding of wild-type p53 to its target sites is accompanied by changes in epigenetic marks like histone acetylation. We studied DNA binding and epigenetic changes...

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Detalles Bibliográficos
Autores principales: Vrba, Lukas, Junk, Damian J, Novak, Petr, Futscher, Bernard W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585595/
https://www.ncbi.nlm.nih.gov/pubmed/18922183
http://dx.doi.org/10.1186/1471-2164-9-486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585595/
https://www.ncbi.nlm.nih.gov/pubmed/18922183
http://dx.doi.org/10.1186/1471-2164-9-486

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