Cargando…
p53 induces distinct epigenetic states at its direct target promoters
BACKGROUND: The tumor suppressor protein p53 is a transcription factor that is mutated in many cancers. Regulation of gene expression by binding of wild-type p53 to its target sites is accompanied by changes in epigenetic marks like histone acetylation. We studied DNA binding and epigenetic changes...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585595/ https://www.ncbi.nlm.nih.gov/pubmed/18922183 http://dx.doi.org/10.1186/1471-2164-9-486 |