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Apoptosis Maintains Oocyte Quality in Aging Caenorhabditis elegans Females
In women, oocytes arrest development at the end of prophase of meiosis I and remain quiescent for years. Over time, the quality and quantity of these oocytes decreases, resulting in fewer pregnancies and an increased occurrence of birth defects. We used the nematode Caenorhabditis elegans to study h...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585808/ https://www.ncbi.nlm.nih.gov/pubmed/19057674 http://dx.doi.org/10.1371/journal.pgen.1000295 |