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Apoptosis Maintains Oocyte Quality in Aging Caenorhabditis elegans Females

In women, oocytes arrest development at the end of prophase of meiosis I and remain quiescent for years. Over time, the quality and quantity of these oocytes decreases, resulting in fewer pregnancies and an increased occurrence of birth defects. We used the nematode Caenorhabditis elegans to study h...

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Detalles Bibliográficos
Autores principales: Andux, Sara, Ellis, Ronald E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585808/
https://www.ncbi.nlm.nih.gov/pubmed/19057674
http://dx.doi.org/10.1371/journal.pgen.1000295