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The N-Terminal Domain of ERK1 Accounts for the Functional Differences with ERK2

The Extracellular Regulated Kinase 1 and 2 transduce a variety of extracellular stimuli regulating processes as diverse as proliferation, differentiation and synaptic plasticity. Once activated in the cytoplasm, ERK1 and ERK2 translocate into the nucleus and interact with nuclear substrates to induc...

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Detalles Bibliográficos
Autores principales: Marchi, Matilde, D'Antoni, Angela, Formentini, Ivan, Parra, Riccardo, Brambilla, Riccardo, Ratto, Gian Michele, Costa, Mario
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585810/
https://www.ncbi.nlm.nih.gov/pubmed/19052640
http://dx.doi.org/10.1371/journal.pone.0003873