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Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord

Adaptor protein (AP) complexes regulate clathrin-coated vesicle assembly, protein cargo sorting, and vesicular trafficking between organelles in eukaryotic cells. Because disruption of the various subunits of the AP complexes is embryonic lethal in the majority of cases, characterization of their fu...

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Detalles Bibliográficos
Autores principales: Montpetit, Alexandre, Côté, Stéphanie, Brustein, Edna, Drouin, Christian A., Lapointe, Line, Boudreau, Michèle, Meloche, Caroline, Drouin, Régen, Hudson, Thomas J., Drapeau, Pierre, Cossette, Patrick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585812/
https://www.ncbi.nlm.nih.gov/pubmed/19057675
http://dx.doi.org/10.1371/journal.pgen.1000296