Cargando…

Activation of a dendritic cell–T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells

The STEP HIV vaccine trial, which evaluated a replication-defective adenovirus type 5 (Ad5) vector vaccine, was recently stopped. The reasons for this included lack of efficacy of the vaccine and a twofold increase in the incidence of HIV acquisition among vaccinated recipients with increased Ad5-ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Perreau, Matthieu, Pantaleo, Giuseppe, Kremer, Eric J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585831/
https://www.ncbi.nlm.nih.gov/pubmed/18981239
http://dx.doi.org/10.1084/jem.20081786