A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity

Hem1 (Hematopoietic protein 1) is a hematopoietic cell-specific member of the Hem family of cytoplasmic adaptor proteins. Orthologues of Hem1 in Dictyostelium discoideum, Drosophila melanogaster, and Caenorhabditis elegans are essential for cytoskeletal reorganization, embryonic cell migration, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Heon, Staehling-Hampton, Karen, Appleby, Mark W., Brunkow, Mary E., Habib, Tania, Zhang, Yi, Ramsdell, Fred, Liggitt, H. Denny, Freie, Brian, Tsang, Mark, Carlson, George, Friend, Sherree, Frevert, Charles, Iritani, Brian M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585840/
https://www.ncbi.nlm.nih.gov/pubmed/19015308
http://dx.doi.org/10.1084/jem.20080340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585840/
https://www.ncbi.nlm.nih.gov/pubmed/19015308
http://dx.doi.org/10.1084/jem.20080340

Ejemplares similares