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The Roles of Pore Ring and Plug in the SecY Protein-conducting Channel

The protein-conducting channel, or translocon, is an evolutionarily conserved complex that allows nascent proteins to cross a cellular membrane or integrate into it. The crystal structure of an archaeal translocon, the SecY complex, revealed that two elements contribute to sealing the channel: a sma...

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Detalles Bibliográficos
Autores principales: Gumbart, James, Schulten, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585858/
https://www.ncbi.nlm.nih.gov/pubmed/19001142
http://dx.doi.org/10.1085/jgp.200810062