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Molecular Template for a Voltage Sensor in a Novel K(+) Channel. III. Functional Reconstitution of a Sensorless Pore Module from a Prokaryotic Kv Channel

KvLm is a prokaryotic voltage-gated K(+) (Kv) channel from Listeria monocytogenes. The sequence of the voltage-sensing module (transmembrane segments S1-S4) of KvLm is atypical in that it contains only three of the eight conserved charged residues known to be deterministic for voltage sensing in euk...

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Detalles Bibliográficos
Autores principales: Santos, Jose S., Grigoriev, Sergey M., Montal, Mauricio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585861/
https://www.ncbi.nlm.nih.gov/pubmed/19029373
http://dx.doi.org/10.1085/jgp.200810077