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Slow Inactivation in Shaker K Channels Is Delayed by Intracellular Tetraethylammonium

After removal of the fast N-type inactivation gate, voltage-sensitive Shaker (Shaker IR) K channels are still able to inactivate, albeit slowly, upon sustained depolarization. The classical mechanism proposed for the slow inactivation observed in cell-free membrane patches—the so called C inactivati...

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Detalles Bibliográficos
Autores principales: González-Pérez, Vivian, Neely, Alan, Tapia, Christian, González-Gutiérrez, Giovanni, Contreras, Gustavo, Orio, Patricio, Lagos, Verónica, Rojas, Guillermo, Estévez, Tania, Stack, Katherine, Naranjo, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585862/
https://www.ncbi.nlm.nih.gov/pubmed/19029372
http://dx.doi.org/10.1085/jgp.200810057