Frameshift mutations in coding repeats of protein tyrosine phosphatase genes in colorectal tumors with microsatellite instability

BACKGROUND: Protein tyrosine phosphatases (PTPs) like their antagonizing protein tyrosine kinases are key regulators of signal transduction thereby assuring normal control of cellular growth and differentiation. Increasing evidence suggests that mutations in PTP genes are associated with human malig...

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Detalles Bibliográficos
Autores principales: Korff, Sebastian, Woerner, Stefan M, Yuan, Yan P, Bork, Peer, von Knebel Doeberitz, Magnus, Gebert, Johannes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586028/
https://www.ncbi.nlm.nih.gov/pubmed/19000305
http://dx.doi.org/10.1186/1471-2407-8-329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586028/
https://www.ncbi.nlm.nih.gov/pubmed/19000305
http://dx.doi.org/10.1186/1471-2407-8-329

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