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Inter-Species Complementation of the Translocon Beta Subunit Requires Only Its Transmembrane Domain

In eukaryotes, proteins enter the secretory pathway through the translocon pore of the endoplasmic reticulum. This protein translocation channel is composed of three major subunits, called Sec61α, β and γ in mammals. Unlike the other subunits, the β subunit is dispensable for translocation and cell...

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Detalles Bibliográficos
Autores principales: Leroux, Alexandre, Rokeach, Luis A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586087/
https://www.ncbi.nlm.nih.gov/pubmed/19057642
http://dx.doi.org/10.1371/journal.pone.0003880