The interferon-γ-mediated inhibition of lipoprotein lipase gene transcription in macrophages involves casein kinase 2- and phosphoinositide-3-kinase-mediated regulation of transcription factors Sp1 and Sp3

The mechanisms underlying transcriptional inhibition by interferon-γ (IFN-γ) are poorly understood despite the existence of a large number of genes that are regulated in this manner and the key role of this cytokine in inflammatory disorders such as atherosclerosis. We have previously identified a n...

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Detalles Bibliográficos
Autores principales: Harris, Sandra M., Harvey, Elizabeth J., Hughes, Timothy R., Ramji, Dipak P.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586094/
https://www.ncbi.nlm.nih.gov/pubmed/18793716
http://dx.doi.org/10.1016/j.cellsig.2008.08.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586094/
https://www.ncbi.nlm.nih.gov/pubmed/18793716
http://dx.doi.org/10.1016/j.cellsig.2008.08.016

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