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Improving peptide-MHC class I binding prediction for unbalanced datasets

BACKGROUND: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such binding could greatly reduce costs and accelerate the experimental process of identifying immunogenic peptides. Many methods...

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Detalles Bibliográficos
Autores principales: Sales, Ana Paula, Tomaras, Georgia D, Kepler, Thomas B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586639/
https://www.ncbi.nlm.nih.gov/pubmed/18803836
http://dx.doi.org/10.1186/1471-2105-9-385