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An Experimental and Computational Study of Effects of Microtubule Stabilization on T-Cell Polarity

T-killer cells eliminate infected and cancerous cells with precision by positioning their centrosome near the interface (immunological synapse) with the target cell. The mechanism of centrosome positioning has remained controversial, in particular the role of microtubule dynamics in it. We re-examin...

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Detalles Bibliográficos
Autores principales: Baratt, Arie, Arkhipov, Sergey N., Maly, Ivan V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586653/
https://www.ncbi.nlm.nih.gov/pubmed/19060950
http://dx.doi.org/10.1371/journal.pone.0003861