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An Experimental and Computational Study of Effects of Microtubule Stabilization on T-Cell Polarity
T-killer cells eliminate infected and cancerous cells with precision by positioning their centrosome near the interface (immunological synapse) with the target cell. The mechanism of centrosome positioning has remained controversial, in particular the role of microtubule dynamics in it. We re-examin...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586653/ https://www.ncbi.nlm.nih.gov/pubmed/19060950 http://dx.doi.org/10.1371/journal.pone.0003861 |