Allergen Uptake, Activation, and IL-23 Production by Pulmonary Myeloid DCs Drives Airway Hyperresponsiveness in Asthma-Susceptible Mice

Maladaptive, Th2-polarized inflammatory responses are integral to the pathogenesis of allergic asthma. As regulators of T cell activation, dendritic cells (DCs) are important mediators of allergic asthma, yet the precise signals which render endogenous DCs “pro-asthmatic”, and the extent to which th...

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Detalles Bibliográficos
Autores principales: Lewkowich, Ian P., Lajoie, Stephane, Clark, Jennifer R., Herman, Nancy S., Sproles, Alyssa A., Wills-Karp, Marsha
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586658/
https://www.ncbi.nlm.nih.gov/pubmed/19060952
http://dx.doi.org/10.1371/journal.pone.0003879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586658/
https://www.ncbi.nlm.nih.gov/pubmed/19060952
http://dx.doi.org/10.1371/journal.pone.0003879

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