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Patterns of evolutionary constraints on genes in humans

BACKGROUND: Different regions in a genome evolve at different rates depending on structural and functional constraints. Some genomic regions are highly conserved during metazoan evolution, while other regions may evolve rapidly, either in all species or in a lineage-specific manner. A strong or even...

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Detalles Bibliográficos
Autores principales: De, Subhajyoti, Lopez-Bigas, Nuria, Teichmann, Sarah A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587479/
https://www.ncbi.nlm.nih.gov/pubmed/18840274
http://dx.doi.org/10.1186/1471-2148-8-275