Cargando…

Patterns of evolutionary constraints on genes in humans

BACKGROUND: Different regions in a genome evolve at different rates depending on structural and functional constraints. Some genomic regions are highly conserved during metazoan evolution, while other regions may evolve rapidly, either in all species or in a lineage-specific manner. A strong or even...

Descripción completa

Detalles Bibliográficos
Autores principales:	De, Subhajyoti, Lopez-Bigas, Nuria, Teichmann, Sarah A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587479/ https://www.ncbi.nlm.nih.gov/pubmed/18840274 http://dx.doi.org/10.1186/1471-2148-8-275

Ejemplares similares

Functional protein divergence in the evolution of Homo sapiens
por: Lopez-Bigas, Nuria, et al.
Publicado: (2008)

Structure-based Markov random field model for representing evolutionary constraints on functional sites
por: Jeong, Chan-Seok, et al.
Publicado: (2016)

Differences in the evolutionary history of disease genes affected by dominant or recessive mutations
por: Furney, Simon J, et al.
Publicado: (2006)

Identification of gene pairs through penalized regression subject to constraints
por: Shen, Rex, et al.
Publicado: (2017)

Discrete Stochastic Optimization for Public Health Interventions with Constraints
por: Li, Zewei, et al.
Publicado: (2022)

Evolutionary triangulation: informing genetic association studies with evolutionary evidence
por: Huang, Minjun, et al.
Publicado: (2016)

BloodExpress: a database of gene expression in mouse haematopoiesis
por: Miranda-Saavedra, Diego, et al.
Publicado: (2009)

USRCAT: real-time ultrafast shape recognition with pharmacophoric constraints
por: Schreyer, Adrian M, et al.
Publicado: (2012)

Evolutionary Constraints on Connectivity Patterns in the Mammalian Suprachiasmatic Nucleus
por: Spencer , Connor, et al.
Publicado: (2021)

Aminode: Identification of Evolutionary Constraints in the Human Proteome
por: Chang, Kevin T., et al.
Publicado: (2018)

Evaluating dosimetric constraints for carbon ion radiotherapy in the treatment of locally advanced pancreatic cancer
por: Lin, Lien-Chun, et al.
Publicado: (2020)

Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints
por: Genikhovich, Grigory, et al.
Publicado: (2015)

GenePattern flow cytometry suite
por: Spidlen, Josef, et al.
Publicado: (2013)

Modularity and evolutionary constraints in a baculovirus gene regulatory network
por: Oliveira, Juliana Velasco, et al.
Publicado: (2013)

Evolutionary concepts in biobanking - the BC BioLibrary
por: Watson, Peter H, et al.
Publicado: (2009)

Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genome
por: Kawaguchi, Risa, et al.
Publicado: (2016)

Automatic construction of metabolic models with enzyme constraints
por: Bekiaris, Pavlos Stephanos, et al.
Publicado: (2020)

Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints
por: Gomez, Andres, et al.
Publicado: (2019)

Design of Synthetic Genetic Oscillators Using Evolutionary Optimization
por: Chang, Yen-Chang, et al.
Publicado: (2013)

Hidden evolutionary constraints dictate the retention of coronavirus accessory genes
por: Goldstein, Stephen A., et al.
Publicado: (2023)

A novel method to identify gene interaction patterns
por: Lu, Xinguo, et al.
Publicado: (2021)

Function and Constraint in Enhancer Sequences with Multiple Evolutionary Origins
por: Fong, Sarah L, et al.
Publicado: (2022)

Identification of genetic interaction networks via an evolutionary algorithm evolved Bayesian network
por: Li, Ruowang, et al.
Publicado: (2016)

Reconstruction of human protein interolog network using evolutionary conserved network
por: Huang, Tao-Wei, et al.
Publicado: (2007)

High-throughput analysis of the transcriptional patterns of sexual genes in malaria
por: Cruz Camacho, Abel, et al.
Publicado: (2023)

Bayesian estimation of gene constraint from an evolutionary model with gene features
por: Zeng, Tony, et al.
Publicado: (2023)

Bayesian estimation of gene constraint from an evolutionary model with gene features
por: Zeng, Tony, et al.
Publicado: (2023)

A possibilistic framework for constraint-based metabolic flux analysis
por: Llaneras, Francisco, et al.
Publicado: (2009)

Evolutionary Constraints to Viroid Evolution
por: Elena, Santiago F., et al.
Publicado: (2009)

Structural and functional properties of genes involved in human cancer
por: Furney, Simon J, et al.
Publicado: (2006)

Formalization of taxon-based constraints to detect inconsistencies in annotation and ontology development
por: Deegan (née Clark), Jennifer I, et al.
Publicado: (2010)

The Evolutionary Constraints on Angiosperm Chloroplast Adaptation
por: Robbins, Elizabeth H J, et al.
Publicado: (2023)

A novel procedure for absolute real-time quantification of gene expression patterns
por: Lu, Yingqing, et al.
Publicado: (2012)

MITOSCISSOR: A Useful Tool for Auto-Assembly of Mitogenomic Datasets in the Evolutionary Analysis of Fishes
por: Sun, Zheng, et al.
Publicado: (2015)

Evolutionary constraints on yeast protein size
por: Warringer, Jonas, et al.
Publicado: (2006)

Influenza emergence in the face of evolutionary constraints
por: Kucharski, Adam, et al.
Publicado: (2012)

Sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs
por: Johnsson, Martin, et al.
Publicado: (2018)

Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
por: Harmanci, Arif Ozgun, et al.
Publicado: (2007)

Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints
por: Dowell, Robin D, et al.
Publicado: (2006)

Evolutionary Developmental Biology and Human Language Evolution: Constraints on Adaptation
por: Fitch, W. Tecumseh
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_0eu0eivc54e2sde41gf2g31cor