MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV

A novel human coronavirus, SARS-CoV, emerged suddenly in 2003, causing approximately 8000 human cases and more than 700 deaths worldwide. Since most animal models fail to faithfully recapitulate the clinical course of SARS-CoV in humans, the virus and host factors that mediate disease pathogenesis r...

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Detalles Bibliográficos
Autores principales: Sheahan, Timothy, Morrison, Thomas E., Funkhouser, William, Uematsu, Satoshi, Akira, Shizou, Baric, Ralph S., Heise, Mark T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587915/
https://www.ncbi.nlm.nih.gov/pubmed/19079579
http://dx.doi.org/10.1371/journal.ppat.1000240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587915/
https://www.ncbi.nlm.nih.gov/pubmed/19079579
http://dx.doi.org/10.1371/journal.ppat.1000240

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