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Disordered Flanks Prevent Peptide Aggregation

Natively unstructured or disordered regions appear to be abundant in eukaryotic proteins. Many such regions have been found alongside small linear binding motifs. We report a Monte Carlo study that aims to elucidate the role of disordered regions adjacent to such binding motifs. The coarse-grained s...

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Detalles Bibliográficos
Autores principales: Abeln, Sanne, Frenkel, Daan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588114/
https://www.ncbi.nlm.nih.gov/pubmed/19096500
http://dx.doi.org/10.1371/journal.pcbi.1000241