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Malleable Machines in Transcription Regulation: The Mediator Complex

The Mediator complex provides an interface between gene-specific regulatory proteins and the general transcription machinery including RNA polymerase II (RNAP II). The complex has a modular architecture (Head, Middle, and Tail) and cryoelectron microscopy analysis suggested that it undergoes dramati...

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Detalles Bibliográficos
Autores principales: Tóth-Petróczy, Ágnes, Oldfield, Christopher J., Simon, István, Takagi, Yuichiro, Dunker, A. Keith, Uversky, Vladimir N., Fuxreiter, Monika
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588115/
https://www.ncbi.nlm.nih.gov/pubmed/19096501
http://dx.doi.org/10.1371/journal.pcbi.1000243