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Malleable Machines in Transcription Regulation: The Mediator Complex
The Mediator complex provides an interface between gene-specific regulatory proteins and the general transcription machinery including RNA polymerase II (RNAP II). The complex has a modular architecture (Head, Middle, and Tail) and cryoelectron microscopy analysis suggested that it undergoes dramati...
Autores principales: | Tóth-Petróczy, Ágnes, Oldfield, Christopher J., Simon, István, Takagi, Yuichiro, Dunker, A. Keith, Uversky, Vladimir N., Fuxreiter, Monika |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588115/ https://www.ncbi.nlm.nih.gov/pubmed/19096501 http://dx.doi.org/10.1371/journal.pcbi.1000243 |
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