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Multiple interactions between the alpha(2C)- and beta(1)-adrenergic receptors influence heart failure survival

BACKGROUND: Persistent stimulation of cardiac β(1)-adrenergic receptors by endogenous norepinephrine promotes heart failure progression. Polymorphisms of this gene are known to alter receptor function or expression, as are polymorphisms of the α(2C)-adrenergic receptor, which regulates norepinephrin...

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Detalles Bibliográficos
Autores principales: Kardia, Sharon LR, Kelly, Reagan J, Keddache, Mehdi A, Aronow, Bruce J, Grabowski, Gregory A, Hahn, Harvey S, Case, Karen L, Wagoner, Lynne E, Dorn, Gerald W, Liggett, Stephen B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588439/
https://www.ncbi.nlm.nih.gov/pubmed/18947427
http://dx.doi.org/10.1186/1471-2350-9-93