An A(2A )adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models

BACKGROUND: The pathophysiology of sepsis is due in part to early systemic inflammation. Here we describe molecular and cellular responses, as well as survival, in A(2A )adenosine receptor (AR) agonist treated and untreated animals during experimental sepsis. METHODS: Sepsis was induced in mice by i...

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Detalles Bibliográficos
Autores principales: Moore, Christopher C, Martin, Edward N, Lee, Grace H, Obrig, Tom, Linden, Joel, Scheld, W Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588444/
https://www.ncbi.nlm.nih.gov/pubmed/18937852
http://dx.doi.org/10.1186/1471-2334-8-141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588444/
https://www.ncbi.nlm.nih.gov/pubmed/18937852
http://dx.doi.org/10.1186/1471-2334-8-141

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